Osteoporosis

Osteoporosis

Why an Osteoporosis Drug Works

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Raloxifene is a U.S. Food and Drug Administration (FDA)-approved treatment for decreasing fracture risk in osteoporosis. While raloxifene is as effective at reducing fracture risk as other current treatments, the medication works only partially by suppressing bone loss. With the use of wide- and small-angle x-ray scattering (WAXS and SAXS, respectively), researchers carried out experiments at the U.S.

Osteoporosis

Surgery to Repair Hip Fracture Saves Billions of $

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Each year, more than 300,000 Americans -- primarily adults over age 65 -- sustain a hip fracture, a debilitating injury that can diminish life quality and expectancy and result in lost work days and substantial, long-term financial costs to patients, families, insurers and government agencies. Surgery, which is the primary treatment for hip fractures, successfully reduces mortality risk and improves physical function. However, little has been known about the procedure's value and return on investment.

Osteoporosis

Oxidative Stress Predicts Hip Fracture

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Oxidative stress -- a disruption in the balance between the production of free radicals and antioxidants -- is a significant predictor for hip fracture in postmenopausal women, according to research led by University of Cincinnati epidemiologists and published online ahead of print in August 2014 in the Journal of Bone and Mineral Research.

Osteoporosis

Progress in Preventing Osteoporosis

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Researchers are progressing in the development of a more effective treatment of osteoporosis, a widespread and serious health problem in the U.S.The investigators, from the UCLA School of Dentistry, are working on a treatment that both slows down the destruction of bone and promotes bone formation.The researchers found that a growth factor, Wnt4, which is secreted in the bone marrow, prevented bone loss in mice with osteoporosis. Wnt4 does that by blocking a signaling pattern that would otherwise promote inflammation.

Osteoporosis

Do You Really Need Vitamin D Supplements?

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You may have heard that researchers who analyzed hundreds of studies have concluded that vitamin D supplements won’t protect healthy, middle-aged adults from osteoporosis. And even worse, the scientists say the supplements may increase the risk of death from other diseases. However, none health experts at the Cleveland Clinic warn that you need to make sure you aren’t deficient in vitamin D before you stop taking the supplement, especially if you are past menopause.

Osteoporosis

Calcium Supplements Don’t Up Heart Risk for Women

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Previous studies have suggested that calcium supplements, which many women take to prevent osteoporosis, may increase risk of cardiovascular disease. However, the data has been inconsistent. A new study by researchers at Brigham and Women's Hospital (BWH) did not find that calcium supplement intake increases risk of cardiovascular disease in women. The article was published online in May 2014 in Osteoporosis International.

Osteoporosis

Fracture Risk Tool Is Flawed

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If you’re between the ages of 40 and 65, or if you’ve ever broken a single bone, the World Health Organization's tool for assessing the likelihood of breaks would underestimate your risk of “fragility fractures” resulting from falls. That is the conclusion of a study done at the University of Sherbrooke in Quebec, Canada  and published in April 2014 published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

Osteoporosis

Too Fit to Fracture

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Experts from the Too Fit to Fracture Initiative have established exercise recommendations for people with osteoporosis, with or without spine fractures. The results were presented at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases in Seville, Spain in April 2014.

Osteoporosis

Osteoporosis and Strength Training

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By Neil Short, Certified Strength and Conditioning Coach Osteoporosis is called the “silent disease” and for good reason. According to the National Osteoporosis Foundation (NOF), more than 50% of women over the age of 50 have it, and few will know until they fall and break a bone. And it doesn’t stop there. The NOF estimates that a full 20% of seniors who break their hip will die within one year from complications due to surgery or recovery, and most end up in nursing homes well before their time.

Osteoporosis

Drug Holidays From Osteoporosis Meds

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Due to the risk of fractures in the thigh bones and tissue decay in the jaw bone associated with osteoporosis drugs known as bisphosphonates, The American Association of Clinical Endocrinologists currently recommends a drug holiday or break from these medications after four to five years of bone density stability if osteoporosis is moderate and after 10 years of stability if fracture risk is high.

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